Matrixyl 200mg (Palmitoyl Pentapeptide-4)

Matrixyl 200mg from Biotech Peptides is a bulk signal peptide for cosmetic formulation research. It’s in stock at $190, with free shipping worldwide on every order. Every batch we sell is synthesized and lyophilized in the USA.

About Matrixyl

Palmitoyl pentapeptide-4 is the five-amino-acid sequence Lys-Thr-Thr-Lys-Ser (KTTKS) with palmitic acid, a 16-carbon fatty acid, attached to one end. KTTKS is a fragment of the C-terminal propeptide of type I procollagen, and the fatty acid is there to help it get through the outer layer of skin.

It was launched as Matrixyl by the French cosmetic ingredient company Sederma in 2000, and it’s still one of the best-known signal peptides in skin care research.

What studies report about Matrixyl

In 1993 Katayama and colleagues reported in the Journal of Biological Chemistry that KTTKS stimulated fibroblasts to produce more type I and type III collagen and fibronectin in culture.

A 12-week, vehicle-controlled study of palmitoyl pentapeptide-4 on facial skin, published by Robinson and colleagues in 2005 in the International Journal of Cosmetic Science, reported improvements in fine lines and wrinkles measured by image analysis.

The full list of Matrixyl papers is on PubMed, and most abstracts are free to read.

How Matrixyl works

Collagen fragments made when old collagen breaks down are thought to act as a feedback signal: they tell fibroblasts that the matrix needs repair. KTTKS mimics one of those fragments.

In fibroblast cultures that signal shows up as more collagen, fibronectin and glycosaminoglycan production. The palmitoyl group makes the peptide more fat-soluble, which matters for how well it crosses skin in topical work.

Matrixyl 200mg at a glance: the specs

• Compound: Matrixyl (palmitoyl pentapeptide-4)
• Other names: Matrixyl, Pal-KTTKS
• CAS number: 214047-00-4
• Molecular formula: C39H75N7O10
• Molecular weight: 802.1 g/mol
• Sequence or structure: Pal-Lys-Thr-Thr-Lys-Ser
• Amount: 200mg
• Form: dry powder for formulation work
• Made: synthesized and lyophilized in the USA
• SKU: Matrixyl-200mg

Using Matrixyl 200mg in formulation work

Scoop or weigh the powder quickly and reseal the pouch or jar. Humidity is the main enemy of a dry peptide, more than heat.

Most cosmetic peptides dissolve in water or in the water phase of a formula. Add them below about 40°C, after the hot steps, so heat doesn’t damage the chain.

Keep the unopened powder frozen. Once you’re working from it, the fridge and a tight seal are enough for a month or so.

Study designs that use Matrixyl 200mg

A typical path starts with cell culture: fibroblasts for matrix proteins, melanocytes for pigment, nerve and muscle co-cultures for expression-line peptides. Reconstructed skin equivalents come after that.

Run a vehicle-only batch beside every peptide batch. Without a control made from the same base, it’s hard to say whether a change came from the peptide or from the cream.

Often ordered with Matrixyl 200mg

• Decapeptide-12 200mg, a tyrosinase-inhibiting peptide
• Vialox 200mg (Pentapeptide-3V), a nicotinic receptor-blocking peptide
• Tripeptide-29 200mg, a collagen tripeptide
• Nonapeptide-1 200mg, an MC1R antagonist peptide

Keep browsing: cosmetic peptides, or the whole Biotech Peptides catalog.

Matrixyl 200mg from a store that sells peptides only

Biotech Peptides is a peptide-only store. You see the price up front, there’s no account required to check out, and if a product page lists a COA, the document is right there in the images. You don’t have to ask for it.

Support is by email, through the contact page. It covers order questions, lot numbers and requests for documents.

Delivery for Matrixyl 200mg orders

Every order ships free, domestic or international. Dry peptide is stable at room temperature for the length of a normal delivery, so there’s no ice pack surcharge. Freeze it once it lands.

Every product is listed in our shop, and the Biotech Peptides Shop home page links to the blog’s country-by-country delivery guides.

Matrixyl 200mg questions and answers

Is Matrixyl 200mg in stock?

Yes. We have it in stock now.

Where can I buy Matrixyl 200mg?

From this page on biotechpeptidesshop.com, the Biotech Peptides store.

Is Matrixyl approved for human use?

No. It’s sold for laboratory research only and isn’t for human or veterinary use.

How much does shipping cost?

Nothing. Shipping is free on every order worldwide.

Is Matrixyl 200mg a vial or a bulk powder?

It’s 200mg of powder for formulation and skin model research, not a reconstitution vial.

Matrixyl 200mg for sale now

Get Matrixyl 200mg for $190. It’s in stock, shipping is free, and the cart button is right above.

Other products for the same work are in the cosmetic peptides section.

For laboratory research only. Not for human or veterinary use, and not evaluated by the FDA.