MOTS-c 10mg

Buy MOTS-c 10mg here at Biotech Peptides: a mitochondrial peptide in a 10mg vial, sealed and freeze-dried. It’s in stock at $99, with free shipping worldwide on every order. Like the rest of our catalog, it’s synthesized and lyophilized in the USA. The lot paperwork (COA, HPLC trace and mass spectrum) is in the product images.

About MOTS-c

MOTS-c is a 16-amino-acid peptide coded not in the cell nucleus but in mitochondrial DNA, inside the gene for the 12S ribosomal RNA. Changhan Lee and colleagues in Pinchas Cohen’s lab at the University of Southern California described it in 2015.

It belongs to a small group of mitochondrial-derived peptides, alongside humanin, that act as signals from the mitochondria to the rest of the cell and body.

MOTS-c in published research

The 2015 Cell Metabolism paper reported that MOTS-c prevented diet-induced obesity and insulin resistance in mice, working mainly through skeletal muscle.

Reynolds and colleagues reported in Nature Communications in 2021 that exercise raises MOTS-c levels in people, and that treating older mice with it improved their physical performance.

Search the original papers yourself on PubMed.

The biology behind MOTS-c

Most proteins are coded in the cell nucleus. MOTS-c is one of a handful of peptides coded in mitochondrial DNA instead. Its main target looks like the folate cycle, which feeds into AMPK activation and better glucose handling in muscle.

Under stress it can move into the nucleus and change gene expression. Circulating levels drop with age in both mice and people, which is why it’s studied in metabolism and aging.

MOTS-c 10mg at a glance: the specs

• Compound: MOTS-c
• CAS number: 1627580-64-6
• Molecular formula: C101H152N28O22S2
• Molecular weight: 2,174.6 g/mol
• Sequence or structure: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
• Amount: 10mg
• Form: lyophilized (freeze-dried) powder
• Made: synthesized and lyophilized in the USA
• Lot paperwork: COA, HPLC and MS images in the gallery
• SKU: MOTS-c-10mg

Lot testing for MOTS-c 10mg

The COA in the gallery covers appearance, molecular weight by mass spec, HPLC purity, assay, solubility and residual TFA and acetic acid for the lot. The raw HPLC and MS plots are there too.

If you need the PDF for a lab notebook or an ethics file, send us the order number and we’ll email it.

How to mix MOTS-c 10mg

The concentration is the 10mg in the vial divided by the water you add:

• 1mL of water: 10mg per mL
• 2mL of water: 5mg per mL
• 3mL of water: 3.33mg per mL

Use sterile bacteriostatic water and add it slowly, aiming at the glass instead of the powder. A gentle swirl is all it needs.

Before mixing, keep it at -20°C and out of the light. After mixing, the fridge at 2 to 8°C, and use it within about four weeks.

Ordering enough MOTS-c 10mg

Work out the total amount the protocol needs first, then add about 20% for test runs and the odd lost dose. Ordering everything from one lot keeps the material consistent through the whole study.

MOTS-c compared with similar peptides

MOTS-c is a 16-amino-acid peptide coded in mitochondrial DNA, studied for glucose use in muscle. If you’re choosing between options, these are the usual alternatives:

• AOD-9604 is hGH fragment 177-191 with an extra tyrosine, studied for fat breakdown without raising IGF-1
• Fragment 176-191 is the fat-metabolism end of growth hormone, without the growth effects
• AICAR is a small molecule that switches on AMPK, the cell’s energy sensor
• Adipotide targets blood vessels that feed fat tissue and was tested in obese monkeys

They all show up in fat metabolism research but start from different places: GH fragments acting on fat cells, energy-sensing pathways inside the cell, and a peptide that targets fat tissue’s blood supply. All of them are on our fat loss peptides page.

Shop more like MOTS-c 10mg

• Tesamorelin Ipamorelin Blend 8mg, with Tesamorelin and Ipamorelin in one vial
• AICAR 50mg, an AMPK activator
• Adipotide (FTPP) 10mg, a fat-targeting peptide
• AOD-9604 5mg, a hGH fragment

See everything in fat loss peptides and longevity peptides, or browse all research peptides from the Biotech Peptides home page.

Why buy MOTS-c 10mg from Biotech Peptides

Our catalog is narrow on purpose: research peptides, blends and cosmetic peptide powders. That keeps stock moving, so the vial you order isn’t one that has been sitting on a shelf for a year.

Problems with an order go through the contact page. Include the order number and a photo of anything damaged.

Free shipping on MOTS-c 10mg

Every order ships free, domestic or international. Dry peptide is stable at room temperature for the length of a normal delivery, so there’s no ice pack surcharge. Freeze it once it lands.

Every product is listed in our shop, and the Biotech Peptides Shop home page links to the blog’s country-by-country delivery guides.

MOTS-c 10mg FAQ

Where can I buy MOTS-c 10mg?

From this page on biotechpeptidesshop.com, the Biotech Peptides store.

Is MOTS-c approved for human use?

No. It’s sold for laboratory research only and isn’t for human or veterinary use.

How much does shipping cost?

Nothing. Shipping is free on every order worldwide.

What do I reconstitute MOTS-c 10mg with?

Sterile bacteriostatic water. The mixing section above lists concentrations for common volumes.

How should MOTS-c 10mg be stored?

Frozen at -20°C while dry. After mixing, in the fridge at 2 to 8°C, used within about four weeks.

Buy MOTS-c 10mg online today

Ready to order? MOTS-c 10mg is $99 and ships free. Use the cart button at the top of the page.

Building a larger order? Browse the fat loss peptides and longevity peptides as well.

For laboratory research only. Not for human or veterinary use, and not evaluated by the FDA.