TRH 25mg (Protirelin)

TRH 25mg from Biotech Peptides is a thyrotropin-releasing hormone (TRH), sold in a 25mg vial of freeze-dried powder. You pay $93 and shipping costs nothing, whether the order goes across the US or overseas. Like the rest of our catalog, it’s synthesized and lyophilized in the USA.

About TRH

Protirelin is synthetic TRH, the three-amino-acid hormone pGlu-His-Pro-NH2 that the hypothalamus uses to tell the pituitary to release TSH.

It was the first hypothalamic hormone to be sequenced, work that earned Roger Guillemin and Andrew Schally part of the 1977 Nobel Prize.

TRH in published research

Protirelin was used for decades as a diagnostic test of the thyroid axis. It also has effects in the brain, and researchers have studied it for arousal, depression and neuroprotection.

Its half-life is only minutes, which is why longer-acting analogs such as taltirelin were developed.

For the primary literature, PubMed lists the TRH studies.

How TRH works

TRH binds TRH receptors on pituitary thyrotroph cells and triggers TSH release, and with it the release of thyroid hormones downstream. It also raises prolactin.

In the brain, TRH receptors are spread well beyond the hypothalamus, which accounts for its stimulant and arousal effects in animal models.

TRH 25mg specifications

• Compound: TRH (protirelin)
• Other names: TRH, thyrotropin-releasing hormone
• CAS number: 24305-27-9
• Molecular formula: C16H22N6O4
• Molecular weight: 362.4 g/mol
• Sequence or structure: pGlu-His-Pro-NH2
• Amount: 25mg
• Form: lyophilized (freeze-dried) powder
• Made: synthesized and lyophilized in the USA
• SKU: TRH-25mg

How to mix TRH 25mg

With 25mg in the vial, common water volumes work out like this:

• 2mL of water: 12.5mg per mL
• 3mL of water: 8.33mg per mL
• 5mL of water: 5mg per mL

Bring the vial to room temperature, add sterile bacteriostatic water against the glass and swirl gently. It should go clear within a minute or two. Shaking only makes foam.

Store sealed vials in the freezer. Once you’ve added water, keep the vial at 2 to 8°C and plan to finish it within roughly a month.

Planning a study with TRH 25mg

Map out the doses per group, multiply by the number of days, and add a margin. It’s cheaper to order one extra vial at the start than to restart a study.

TRH vs related compounds

TRH is synthetic TRH, the signal for thyroid-stimulating hormone. If you’re choosing between options, these are the usual alternatives:

• PT-141 is a melanocortin agonist derived from Melanotan II, acting on MC4 receptors in the brain
• Kisspeptin-10 sits at the top of the reproductive axis and triggers GnRH release
• Oxytocin is the nine-amino-acid hormone behind labor, milk release and social bonding
• Gonadorelin is synthetic GnRH, the hypothalamic signal for LH and FSH
• Triptorelin is a long-acting GnRH agonist that first stimulates, then shuts down, LH and FSH

Each acts on its own hormone axis, so one can’t stand in for another. All of them are on our hormone peptides page.

Related hormone peptides

• Oxytocin 10mg, a neuropeptide hormone
• Kisspeptin-10 10mg, a neuropeptide
• Triptorelin 2mg, a GnRH agonist
• Gonadorelin (GnRH) 10mg, a synthetic GnRH

The full range is on the research peptides page. For this research area, go to hormone peptides.

TRH 25mg from a store that sells peptides only

We sell research peptides and nothing else, close to 90 of them, so questions about TRH 25mg reach people who handle these products every day. Orders are packed from stock, and every listing shows its real price No membership, no minimum order.

If something arrives damaged or isn’t what you ordered, tell us soon after delivery. Photos of the parcel and the vial make it quicker to sort out.

Shipping TRH 25mg worldwide

Shipping is free on every order, to the US, Canada, the UK, Europe, Australia and the other countries we serve. Freeze-dried peptide handles normal transit temperatures, so it travels in standard packaging and goes into the freezer when it arrives.

Every product is listed in our shop, and the Biotech Peptides Shop home page links to the blog’s country-by-country delivery guides.

TRH 25mg questions and answers

How should TRH 25mg be stored?

Frozen at -20°C while dry. After mixing, in the fridge at 2 to 8°C, used within about four weeks.

Is TRH 25mg in stock?

Yes, it’s in stock today.

Where can I buy TRH 25mg?

Order it on this page. We sell direct, so there’s no reseller markup.

Is TRH approved for human use?

No. It’s sold for laboratory research only and isn’t for human or veterinary use.

How much does shipping cost?

Nothing. Shipping is free on every order worldwide.

Buy TRH 25mg online today

Ready to order? TRH 25mg is $93 and ships free. Use the cart button at the top of the page.

Add other compounds from our hormone peptides to the same parcel.

For laboratory research only. Not for human or veterinary use, and not evaluated by the FDA.