MGF 5mg (Mechano Growth Factor)

Buy MGF 5mg here at Biotech Peptides: an IGF-1 splice variant peptide in a 5mg vial, sealed and freeze-dried. The price is $59, it’s in stock, and shipping is free to any country we deliver to. Like the rest of our catalog, it’s synthesized and lyophilized in the USA. The lot paperwork (COA, HPLC trace and mass spectrum) is in the product images.

MGF at a glance

Mechano growth factor is a version of IGF-1 that muscle makes after mechanical load or damage. It comes from alternative splicing of the IGF-1 gene and is called IGF-1Ec in humans. The research peptide is a synthetic copy of its unique E-domain tail, 24 amino acids long.

Geoffrey Goldspink’s group at the Royal Free Hospital in London described it in the 1990s and gave it the name.

MGF research so far

Yang and Goldspink reported in FEBS Letters in 2002 that the MGF E-peptide made muscle satellite cells divide more, separately from the main IGF-1 receptor.

Later studies looked at it in heart and nerve injury models. Some groups couldn’t reproduce every result, so the field still argues about how much of it acts on its own. All of the work is in cells and animals.

The full list of MGF papers is on PubMed, and most abstracts are free to read.

The biology behind MGF

When muscle is stretched or damaged, the IGF-1 gene is spliced differently and makes MGF first, before the main IGF-1 form. The idea is that MGF’s E-domain wakes up satellite cells, the muscle stem cells that repair fibers.

The synthetic E-peptide has no IGF-1 receptor binding domain, so any effect it has is meant to come through a different, still unidentified route. Free MGF peptide also breaks down within minutes, which is why a pegylated version exists.

MGF 5mg specifications

• Compound: MGF
• Other names: mechano growth factor, IGF-1Ec E-peptide
• Molecular formula: C121H200N42O39
• Sequence or structure: Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-His-Lys
• Amount: 5mg
• Form: lyophilized (freeze-dried) powder
• Made: synthesized and lyophilized in the USA
• Lot paperwork: COA, HPLC and MS images in the gallery
• SKU: MGF-5mg

MGF 5mg certificate of analysis

The COA in the gallery covers appearance, molecular weight by mass spec, HPLC purity, assay, solubility and residual TFA and acetic acid for the lot. The raw HPLC and MS plots are there too.

If you need the PDF for a lab notebook or an ethics file, send us the order number and we’ll email it.

MGF 5mg reconstitution and storage

With 5mg in the vial, common water volumes work out like this:

• 1mL of water: 5mg per mL
• 2mL of water: 2.5mg per mL
• 3mL of water: 1.67mg per mL

Use sterile bacteriostatic water and add it slowly, aiming at the glass instead of the powder. A gentle swirl is all it needs.

Before mixing, keep it at -20°C and out of the light. After mixing, the fridge at 2 to 8°C, and use it within about four weeks.

Planning a study with MGF 5mg

Count the total milligrams across every group and time point, and round up. Running out halfway and switching lots adds a variable you didn’t plan for.

MGF vs related compounds

MGF is the E-domain peptide from the muscle-specific IGF-1 splice variant. If you’re choosing between options, these are the usual alternatives:

• IGF-1 LR3 is an 83-amino-acid IGF-1 analog that avoids binding proteins and lasts for hours
• PEG-MGF is MGF with a PEG chain added so it lasts much longer
• ACE-031 is a decoy activin receptor that soaks up myostatin
• Follistatin-344 binds myostatin and activin directly

Muscle research uses two routes: the IGF-1 side (IGF-1 LR3 and the MGF peptides) and the myostatin side (ACE-031 and follistatin). All of them are on our muscle peptides page.

Often ordered with MGF 5mg

• IGF-1 LR3 100mcg (Receptor Grade), an IGF-1 analog
• ACE-031 1mg, a soluble activin receptor fusion protein
• Follistatin-344 1mg, an activin-binding glycoprotein
• PEG-MGF 5mg, a pegylated MGF

See everything in muscle peptides and BPC-157 and recovery peptides, or browse all research peptides from the Biotech Peptides home page.

Why buy MGF 5mg from Biotech Peptides

We sell research peptides and nothing else, close to 90 of them, so questions about MGF 5mg reach people who handle these products every day. Orders are packed from stock, and every listing shows its real price No membership, no minimum order.

If something arrives damaged or isn’t what you ordered, tell us soon after delivery. Photos of the parcel and the vial make it quicker to sort out.

Delivery for MGF 5mg orders

Shipping is free on every order, to the US, Canada, the UK, Europe, Australia and the other countries we serve. Freeze-dried peptide handles normal transit temperatures, so it travels in standard packaging and goes into the freezer when it arrives.

Every product is listed in our shop, and the Biotech Peptides Shop home page links to the blog’s country-by-country delivery guides.

MGF 5mg questions and answers

How much does shipping cost?

Nothing. Shipping is free on every order worldwide.

What do I reconstitute MGF 5mg with?

Sterile bacteriostatic water. The mixing section above lists concentrations for common volumes.

How should MGF 5mg be stored?

Frozen at -20°C while dry. After mixing, in the fridge at 2 to 8°C, used within about four weeks.

Does MGF 5mg come with a COA?

Yes. The certificate of analysis, HPLC trace and mass spectrum for the lot are in the product images.

Is MGF 5mg in stock?

Yes. We have it in stock now.

MGF 5mg for sale now

MGF 5mg is in stock at $59, with free shipping. Add it to your cart above and check out in a couple of minutes.

Other products for the same work are in the muscle peptides and BPC-157 and recovery peptides section.

For laboratory research only. Not for human or veterinary use, and not evaluated by the FDA.